Causes of Cerebral Palsy: Origins, Etiology, Aetiology, Causal Pathways
Cerebral Palsy
Cerebral Palsy
Cerebral Palsy
Cerebral Palsy
Cerebral Palsy
Cerebral Palsy
Cerebral Palsy
Cerebral Palsy
Cerebral Palsy
Cerebral Palsy
Cerebral Palsy
Cerebral Palsy
Cerebral Palsy
Cerebral Palsy
Cerebral Palsy
Cerebral Palsy
Cerebral Palsy
Cerebral Palsy
“Genetic clotting defects are increasingly being implicated in fetal cerebrovascular accidents with resulting porencephalic cysts and even hydranencephaly (Thorarensen et al. 1997, Debus et al. 1998). Further research into detecting these defects (such as factor V Leiden and maternal antiphospholipid antibodies) may eventually elucidate preventable pathways. A controlled trial comparing aspirin with aspirin plus heparin for women with previously affected pregnancies has already commenced (Perinatal Trials Group 1998).

-Stanley, Blair & Alberman

Cerebral Palsy

Cerebral Palsy
There are a number of other variables or risk factors associated with the development of cerebral palsy. They include infant thyroid hormone levels, coagulation disorders or clotting defects in the mother or infant, vaginal bleeding, hypocalcaemia, polycythaemia, hypoglycaemia in infants, the mother being exposed to radiation or methylmercury and delivery room depression.

Over 400 premature babies were discovered to have lower than normal levels of thyroxine and a correlated higher risk of cerebral palsy. Thyroxine is thyroid hormone. This hormone in low levels this is called hypothyroxinemia. It has not been concluded whether this is a sign of the condition or a cause.

Infants weighing 1500 g issuing from a mother exhibiting vaginal bleeding at the time of admission were significantly more likely to evolve cerebral palsy if they were more than 29 weeks into gestation.

In Britian is has been reported that premature infants with hypoglycaemia were increasingly likely to acquire cerebral palsy as their blood sugar decreased.

If a mother is undergoing radiotherapy, CP may be engendered by the intervention. Radian exposure in other contexts can have the same result. There have been several cases where localized environmental damage has resulted in fetus catamination, for example methylmercury poisoning, and the child contracting cerebral palsy.


Stanton, Marion, (2002) The Cerebral Palsy Handbook. Vermillion

Stanley, Fiona, Blair, Eve, Alberman, Eva. (2000) Cerebral Palsies: Epidemiology & Causal Pathways. Mac Keith Press •

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Causes of Cerebral Palsy: Origins, Etiology, Aetiology, Causal Pathways